Joint Studies

ACell Vet Canine Arthritic Joint Study Abstract

“Many dogs are troubled by arthritic joint pain in the hip, particularly as they age. The disease and associated pain creates multiple problems that may include daily medication, on-going veterinary expenses, occasional development of resistance to medical therapy, limits on activities and range of motion, and general degradation of the dog’s quality of life. The present study evaluated the utility of a bio-inductive scaffold derived from porcine bladder extracellular matrix (UBM-ECM) from ACell Vet, Inc. when injected directly into the intra-articular joint space in the canine patient with impairing ambulation due to recurrent joint pain. This study showed results from a single injection that ranged from dramatically alleviating to completely eliminating pain, including excellent improvement in mobility and attitude in the majority of treated animals for a mean duration of 148 days (median value = 168 days). A control group, which was injected with the carrier alone (saline), showed poor results in improving mobility, alleviating pain or even improving the attitude in the animals for a mean duration of 22 days (median value = 14.5 days). We conclude that the injection of particulate UBM-ECM into the intra-articular joint space of the hip is an effective therapy for joint pain in the canine patient.

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ACell Vet Canine Arthritic Joint Study

Summary
Many dogs are troubled by arthritic joint pain in the hip, particularly as they age. The disease and associated pain creates multiple problems that may include daily medication, on-going veterinary expenses, occasional development of resistance to medical therapy, limits on activities and range of motion, and general degradation of the dog’s quality of life. The present study evaluated the utility of a bio-inductive scaffold derived from porcine bladder extracellular matrix (UBM-ECM) from ACell Vet, Inc. when injected directly into the intra-articular joint space in the canine patient with impairing ambulation due to recurrent joint pain. This study showed results from a single injection that ranged from dramatically alleviating to completely eliminating pain, including excellent improvement in mobility and attitude in the majority of treated animals for a mean duration of 148 days (median value = 168 days).

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